Microbiology paper #3
This article discusses the evolution of the pneumonia and how antibiotic have helped this happen. There is a little history on pneumonia and some research, dating 1984-2000. Some statistics, as to how many children have been infected, and or have died. This superbug is mutating faster then we can make vaccines to cover all the different strands.
The microbiology aspect of this paper is very interesting. A strain of pneumonia that was not killed by antibiotics, has stated to mutate, and mutates every 15 weeks. This ?genetic trick? , as they call it, of changing DNA to out whit antibiotics. Every time the strand changes (mutates), there is more resistance to antibiotic therapy. Even more disturbing then that, every time DNA changes, then we have potentially, a new version of itself. The bacteria will enter the immune system in a polysaccharide capsule, 23F. Every time that the DNA changes, the polysaccharide capsule makeup changes as well, this is why vaccines are so outdated. As soon as we get a vaccine on the market, the bacteria has already evolved. When a vaccine is made for a certain strand, then that is all it will fight, therefore all of the newly constituted strains will not be touched by said vaccine.
I found this article very interesting; I know that I have been told you can?t catch the same bug twice. I always wondered how people could get the same thing over and over, if it wasn?t the same bug. This article has helped me understand that, bacteria can evolve and you can potentially, get the same sickness more then once, and that is why. So even though you may have the same diagnosis as the last time, you probably don?t have the same bug. The other ting that I have learned, is that the over prescribing of antibiotic therapy will help bacteria evolve, and potentially have bacteria turn into a superbug, which may not be treatable in the end.
Tina Hesman Saey, Pneumonia drugs helped evolve a superbug,
http://www.sciencenews.org/view/generic/id/69205/title/Pneumonia_drugs_helped_evolve_a_superbug, February 26, 2011